Single-cell characterization of human periodontal ligament (PDL) cells reveals uniformly mesenchymal populations in matched maxilla and mandible pairs from four donors
Chloé Radermacher, Robert Dzhanaev, Christian Hasberg, Sabine Neuß-Stein, Andrea Gorgels, Julia Moellmann, Nikolaus Marx, Anne Babler, Christoph Kuppe, Rogerio Bastos Craveiro, Michael Wolf, Ali Modabber, Willi Jahnen‐Dechent, Isabel Knaup
The paper uses single-cell RNA sequencing to analyze PDL cells from maxilla and mandible pairs, finding uniform mesenchymal populations with donor-specific substates and limited jaw-related transcriptional differences.
bioRxiv · Sep 8, 2026 · PreprintGenomics