Nikolaus Marx

The paper uses single-cell RNA sequencing to analyze PDL cells from maxilla and mandible pairs, finding uniform mesenchymal populations with donor-specific substates and limited jaw-related transcriptional differences.

This study identifies polyploid cardiomyocytes as disease-specific transcriptional states in the mammalian heart and suggests targeting them for heart failure treatment.

This study investigates the role of PDGFR-{beta} in uremic vascular calcification using ex vivo and in vivo models, showing that PDGFR-{beta} activation promotes calcification and VSMC phenotypic switching.

This paper introduces Swarm Learning, a decentralized machine learning approach for disease classification using transcriptomic data, demonstrating its effectiveness in developing classifiers for COVID-19, tuberculosis, and leukemias while preserving privacy.