Author

Robert E. Coffman

University of UtahORCID 0000-0001-8393-2062Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:deep learning· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

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Andrew L. FergusoniD· 1 shared Siva DasettyiD· 1 shared Tamara C. BidoneiD· 1 shared

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2025-2025 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBiophysics

Andrew L. FergusonORCID

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1 paper

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BiophysicsBiophysical JournalPeer-reviewedAug 18, 2025

Prediction of αIIbβ3 integrin structures along its minimum free energy activation pathway

Siva Dasetty, Robert E. Coffman, Tamara C. Bidone, Andrew L. Ferguson

This paper predicts the structures of αIIbβ3 integrin along its minimum free energy activation pathway using a computational method, revealing correlated subdomain movements and providing insights for therapeutic design.

DOI 10.1016/j.bpj.2025.08.013

protein structuredeep learning

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