Tamara C. Bidone

This paper develops a coarse-grained model to study protofilament clustering at microtubule plus-end tips, showing lattice instability drives PF cluster formation and dynamics.

This paper identifies hydrogen peroxide-driven catalytic motion of hemozoin crystals in malaria parasites, revealing them as self-propelled nanoparticles that reduce oxidative stress.

This paper predicts the structures of αIIbβ3 integrin along its minimum free energy activation pathway using a computational method, revealing correlated subdomain movements and providing insights for therapeutic design.

This study uses multiscale modeling to show that microtubule plus-end tips bend outward into curved structures regardless of GTP hydrolysis state, challenging existing models linking curvature to nucleotide state.

This paper uses an equation-free method to accelerate all-atom simulations of microtubule tips, revealing structural differences between GDP- and GTP-bound states.