Author

Cole Mathis

Arizona State UniversityORCID 0000-0001-8424-9169Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:metagenomics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Organism:yeast· 1

Frequent Co-Authors

Sara Imari WalkeriD· 2 shared Christopher P. KempesiD· 1 shared Harrison B. SmithiD· 1 shared Hyunju KimiD· 1 shared Jason RaymondiD· 1 shared Veronica MierzejewskiiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersBiochemistry

Sara Imari WalkerORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJun 20, 2025

Convergent Functional Constraints Make Biochemical Reaction Diversity Predictable

Veronica Mierzejewski, Cole Mathis, Christopher P. Kempes, Sara Imari Walker

The paper shows that biochemical reaction diversity across organisms follows predictable scaling patterns, revealing convergent functional constraints independent of phylogeny or reaction identity.

DOI 10.1101/2025.06.20.660822

bacteria (other)yeast

𝕏 PostBluesky

Systems BiologyScience AdvancesPeer-reviewedJan 4, 2019

Universal scaling across biochemical networks on Earth

Hyunju Kim, Harrison B. Smith, Cole Mathis…·Sara Imari Walker

The paper constructs global biochemical networks from genomes and reactions to reveal universal scaling laws across biological organization levels.

42 citations

metagenomicsstatistical model

𝕏 PostBluesky