Pathway-informed Universal Domain Adaptation for Single-cell RNA-seq Data
Xinrong Wei, Xingyi Li, Huan Liu, Gaoyuan Du, Feng Wei, Xuequn Shang
This paper introduces scPathOT, a pathway-informed domain adaptation method for single-cell RNA-seq data, demonstrating its ability to accurately annotate cell types and uncover functional mechanisms across diverse biological contexts.
bioRxiv · May 11, 2026 · PreprintBioinformatics