Small extracellular vesicles mediate the antihyperalgesic effect of bone marrow stromal cells: the role of "priming"
Wei Guo, Jia-Le Yang, Huakun Xu, Kamal D. Moudgil, Feng Wei, Ke Ren
This study shows that bone marrow stromal cell-derived small extracellular vesicles reduce neuropathic pain in mice, with their efficacy enhanced by prior exposure to injury conditions.
bioRxiv · May 12, 2026 · PreprintNeuroscience