Author

Huan Liu

Westlake University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioinformatics· 3 Physiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:spatial transcriptomics· 2

Frequent Co-Authors

Jinhong Lu· 2 shared Mengdie Yao· 2 shared Nan Li· 2 shared Qing Yang· 2 shared Xing Wu· 2 shared Yanmei DouiD· 2 shared Yiheng Du· 2 shared Yonghe Xia· 2 shared

Activity by Year

2018-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioinformatics

Jinhong Lu

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5 papers

Recent·Most cited

The cellular and genetic basis of inflorescence divergence between maize and teosinte

Yuebin Wang, Ruijie Mao, Yu Liu, Xing Guo, Nan Li, Qian Zhang, Manjun Cai, Xie Pingli, Yi Wang, Yun Luo, Qian Ding, Shenshen Wu, En Luo, Ling Ma, Zheng Luo, , Ning Yang

This study identifies cellular and genetic changes in maize and teosinte ears, showing how cytokinin signaling and transcription factor expression differences drive cob thickening and increased kernel number during domestication.

bioRxiv · Aug 27, 2026 · PreprintPlant Biology

Pathway-informed Universal Domain Adaptation for Single-cell RNA-seq Data

Xinrong Wei, Xingyi Li, Huan Liu, Gaoyuan Du, Feng Wei, Xuequn Shang

This paper introduces scPathOT, a pathway-informed domain adaptation method for single-cell RNA-seq data, demonstrating its ability to accurately annotate cell types and uncover functional mechanisms across diverse biological contexts.

bioRxiv · May 11, 2026 · PreprintBioinformatics

Detection of Somatic Point Mutations Directly from Spatial Transcriptomics Enables in vivo Spatiotemporal Lineage Tracing

Zhirui Yang, Mengdie Yao, Qing Yang, Yiheng Du, Jinhong Lu, Xing Wu, Jinran Lin, Zhuoyu Qian, Song Hu, Yonghe Xia, Huan Liu, Qiji Zhou, Xiaoyu Ma, Yan Luo, Wenxuan Fan, , Yanmei Dou

SpaceTracer detects somatic SNVs from spatial transcriptomics data to enable lineage tracing in human tissues, revealing tumor progression and immune cell migration.

bioRxiv · Feb 6, 2026 · PreprintBioinformatics

PhyloSOLID: Robust phylogeny reconstruction from single-cell data despite inherent error and sparsity

Qing Yang, Yuheng Liu, Jijian Yang, Xing Wu, Zhirui Yang, Yonghe Xia, Yunchao Zheng, Jinhong Lu, Mengdie Yao, Yiheng Du, Huan Liu, Nan Li, Yanmei Dou

PhyloSOLID improves phylogenetic reconstruction from single-cell data by addressing error and sparsity, achieving better accuracy than existing methods.

bioRxiv · Feb 6, 2026 · PreprintBioinformatics

Chicken uric acid elimination via the uric acid transporters BCRP and MRP4 in the liver, kidneys, and intestines

Xuedong Ding, Manman Li, Shoufa Qian, Yuying Ma, Tianyi Fang, Xinlu Li, Huan Liu, Shibin Feng, Yu Li, Xichun Wang, Jinchun Li, Jinjie Wu

This study investigates the role of BCRP and MRP4 in chicken uric acid excretion across liver, kidneys, and intestines under different dietary and physiological conditions.

bioRxiv · Jul 18, 2018 · PreprintPhysiology