Cancer BiologyDevelopmental CellPeer-reviewed
Solid tumor growth depends on an intricate equilibrium of malignant cell states
Stefan R. Torborg, Jung Yun Kim, Anupriya Singhal…·Tuomas Tammela
This study identifies a stereotypic organization of pancreatic ductal adenocarcinoma cells based on WNT signaling and Notch ligand interactions, showing that disrupting this equilibrium suppresses tumor growth and metastasis.
6 citations