Matthis Ebel

BRAKER3 improves eukaryotic genome annotation by integrating RNA-seq, protein data, and statistical models, achieving higher accuracy than previous tools.

GALBA is a fully automated gene annotation pipeline combining miniprot and AUGUSTUS, achieving high accuracy in large vertebrate genomes and new species.

The paper introduces geometric hashing, a method to filter alignment seeds with high specificity and efficiency, reducing false positives in homology searches across human and mouse genomes.