Author

Samuel J. Chen

University of MichiganORCID 0000-0001-8501-7175Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 1

Frequent Co-Authors

Allen P. LiuiD· 2 shared Hossein MoghimianavvaliD· 2 shared Alexander J. Huang· 1 shared Andrew L. FergusoniD· 1 shared Ayush PandaiD· 1 shared Bineet SharmaiD· 1 shared Daniel H. Zhou· 1 shared Jianming MaoiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersSynthetic Biology

Allen P. LiuORCID

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2 papers

Recent·Most cited

Cytoplasmic Abundant Heat-Soluble Proteins from Tardigrades Protect Synthetic Cells Under Stress

Yongkang Xi, Jianming Mao, Samuel J. Chen, Hossein Moghimianavval, Young Jin Lee, Ayush Panda, Alexander J. Huang, Daniel H. Zhou, L. Andy Xu, Kayla Y. Fu, Solomon Adera, Andrew L. Ferguson, Allen P. Liu

The paper shows CAHS12 proteins protect synthetic cells under stress by forming a network that maintains membrane integrity and preserves encapsulated components.

Nature Communications · May 2, 2026Peer-reviewedSynthetic Biology

Calcium-triggered DNA-mediated membrane fusion in synthetic cells

Yen-Yu Hsu, Samuel J. Chen, Julio Bernal‐Chanchavac, Bineet Sharma, Hossein Moghimianavval, Nicholas Stephanopoulos, Allen P. Liu

This paper develops a calcium-triggered DNA-mediated membrane fusion strategy using surface-bound PEG chains cleavable by calpain-1.

Chemical Communications · Jan 1, 2023Peer-reviewedSynthetic Biology