Hossein Moghimianavval

This study develops a cell-free biosensing reporter using rapalog-induced split sfCherry reconstitution and demonstrates steric attenuation of fluorescence by antibodies binding to epitope tags.

This paper shows that a synthetic gene circuit can break a growth rate plateau in E. coli by selectively suppressing slow-growing cells, leading to faster growth.

The paper shows CAHS12 proteins protect synthetic cells under stress by forming a network that maintains membrane integrity and preserves encapsulated components.

The paper investigates how heterogeneity in PhoP expression affects downstream gene activation and antimicrobial peptide tolerance in E. coli.

This paper designs and experimentally validates biomolecular neural networks using molecular sequestration, demonstrating their ability to function as linear classifiers in living systems.

This paper introduces TRAP, a light-triggered protease system for controlled secretion from synthetic cells, demonstrating its ability to release fluorescent and luminescent proteins.

This paper demonstrates a light-activated contact-dependent communication system between synthetic cells using split bioluminescent proteins and photoswitchable proteins.

This paper designs sigma factor-based biomolecular classifiers and investigates how resource competition affects their performance and design principles.

This paper develops a calcium-triggered DNA-mediated membrane fusion strategy using surface-bound PEG chains cleavable by calpain-1.

The paper introduces InterSpy, a synthetic biology tool that forms membrane-membrane interfaces using SpyTag/SpyCatcher, and demonstrates its function in cell-free systems and cells.