NeurosciencebioRxivPreprint
Lipid droplets promote the aberrant liquid-liquid phase separation of alpha-synuclein leading to impaired energy homeostasis
Jose Cevallos, Elena Eubanks, Sunghoo Jung…·Eleanna Kara
This study shows lipid droplets promote alpha-synuclein phase separation, leading to mitochondrial toxicity and neurodegeneration in Parkinson's disease.