Author

Matthew L. Fidler

Novartis (United States)ORCID 0000-0001-8538-6691Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

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Approach:statistical model· 1

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Hidde van de BeekiD· 1 shared J. G. Coen van HasseltiD· 1 shared Laura B. ZwepiD· 1 shared Massinissa BeldjennaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperPharmacology & Toxicology

Hidde van de BeekORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintJul 15, 2026

From exact gradients to exact standard errors: third- and fourth-order sensitivities for the Laplacian population likelihood family

Hidde van de Beek, Massinissa Beldjenna, Matthew L. Fidler…·J. G. Coen van Hasselt

This paper derives exact standard errors for Laplacian population likelihood models using third- and fourth-order sensitivities, avoiding finite differencing and empirical Bayes reoptimization.

DOI 10.64898/2026.07.09.737434

statistical model

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