Laura B. Zwep

This study examines how phage resistance in Pseudomonas aeruginosa affects antibiotic sensitivity, finding strain- and antibiotic-specific collateral effects.

This paper derives exact standard errors for Laplacian population likelihood models using third- and fourth-order sensitivities, avoiding finite differencing and empirical Bayes reoptimization.

This study uses circuit topology to analyze protein folding, showing that ordered and disordered proteins differ in topological organization and that topology predicts folding state and kinetics.

The paper implements an aggregate data modelling framework in R, introducing an efficient algorithm that significantly speeds up pharmacometric model fitting while maintaining accuracy.