Peter De Rijk

Scywalker: scalable end-to-end data analysis workflow for nanopore single-cell transcriptome sequencing

Scywalker provides a scalable analysis pipeline for nanopore single-cell transcriptome data, showing good correlation with short-read analyses and enabling isoform-level cell-type-specific expression identification.

Accurate characterization of expanded tandem repeat length and sequence through whole genome long-read sequencing on PromethION.

This paper develops a method to accurately characterize expanded tandem repeats using long-read sequencing on PromethION, outperforming traditional methods and enabling clinical applications.

Structural variants identified by Oxford Nanopore PromethION sequencing of the human genome

The paper benchmarks structural variant calling tools using Oxford Nanopore PromethION sequencing of the human genome, finding Minimap2 and Sniffles to be the most accurate and efficient.

opentsv prevents the corruption of scientific data byExcel

Opentsv prevents Excel from corrupting scientific data by allowing safe opening of delimited data files without name conversions.

Critical length in long read resequencing

This study determines the optimal read length for structural variant discovery and haplotyping using long-read sequencing in human genomes.