Rajeev Mishra

This paper identifies transcriptomic, miRNA, and CAF-associated reprogramming in EML4-ALK fusion-positive NSCLC compared to fusion-negative tumors.

This study identifies a fusion-driven post-transcriptional network in PRCC-TFE3 tumors that regulates ferroptosis resistance, dormancy, and immune remodeling through miRNA-mRNA interactions.

The paper integrates multi-omics data from 14 cancers to reveal early metabolic and transcriptional reprogramming in the tumor microenvironment, identifying key genes and pathways involved.

This study identifies immune suppression and metabolic reprogramming in FGFR3-TACC3 fusion-positive bladder cancer through transcriptomic and miRNA analysis, revealing fusion-specific regulatory interactions and potential therapeutic targets.

The paper investigates how endogenous pancreatic microRNAs differentially target SARS-CoV-2 variants (Delta, Omicron, Wuhan) and upregulate diabetes-associated genes despite UTR mutations.

The paper identifies five diabetes-associated genes upregulated in SARS-CoV-2-infected pancreatic tissue and hypothesizes that miRNA competition between viral and host genes contributes to diabetes exacerbation in COVID-19.

The paper investigates the role of the SARS-CoV-2 infected pancreas secretome in multi-organ dysfunctions using scRNA-seq and identifies upregulated genes and secretory proteins linked to various organ systems and diseases.