Author

Kuei-Yueh Ko

Duke UniversityORCID 0000-0001-8564-8524Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alejandro BarreraiD· 1 shared Alexander ThomsoniD· 1 shared Andrew S. AlleniD· 1 shared Boyao LiiD· 1 shared Hilmar LappiD· 1 shared Katherine DuraiD· 1 shared R Doty· 1 shared Revathy VenukuttaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Alejandro BarreraORCID

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1 paper

Recent·Most cited

Modeling gene regulatory perturbations via deep learning from high-throughput reporter assays

Revathy Venukuttan, R Doty, Alexander Thomson, Yutian Chen, Boyao Li, Yuncheng Duan, Alejandro Barrera, Katherine Dura, Kuei-Yueh Ko, Hilmar Lapp, Timothy E. Reddy, Andrew S. Allen, William H. Majoros

The paper introduces BlueSTARR, a predictive modeling framework trained on whole-genome STARR-seq data to assess variant effects on regulatory functions, revealing purifying selection against loss-of-function and gain-of-function variants.

bioRxiv · Mar 31, 2026 · PreprintBioinformatics