Author

Yutian Chen

Scripps Research InstituteORCID 0009-0008-1205-0618Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alejandro BarreraiD· 1 shared Alexander ThomsoniD· 1 shared Andrew S. AlleniD· 1 shared Boyao LiiD· 1 shared Hilmar LappiD· 1 shared Katherine DuraiD· 1 shared Kuei-Yueh KoiD· 1 shared R Doty· 1 shared

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2026-2026 · peak 1/yr

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Alejandro BarreraORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintMar 31, 2026

Modeling gene regulatory perturbations via deep learning from high-throughput reporter assays

Revathy Venukuttan, R Doty, Alexander Thomson…·William H. Majoros

The paper introduces BlueSTARR, a predictive modeling framework trained on whole-genome STARR-seq data to assess variant effects on regulatory functions, revealing purifying selection against loss-of-function and gain-of-function variants.

DOI 10.64898/2026.03.27.714770

humanDNA methylation

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