Author

Helena Mira

Consejo Superior de Investigaciones CientíficasORCID 0000-0001-8574-9544Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Lucía Casares-CrespoiD· 3 shared Alba Ripolles-BoixiD· 1 shared Carmina Franch-IbáñeziD· 1 shared Elena Juárez‐EscotoiD· 1 shared Fabián Robledo-YagüeiD· 1 shared Isabel Calatayud-BaselgaiD· 1 shared José Guijarro-NueziD· 1 shared Marifé Cano‐JaimeziD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersNeuroscience

Lucía Casares-CrespoORCID

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3 papers

Recent·Most cited

NeuroscienceGliaPeer-reviewedSep 24, 2026

Cell surface markers identify astrocyte subpopulations in the adult hippocampus with a heterogeneous response to aging

Lucía Casares-Crespo, Marifé Cano‐Jaimez, Raquel Anta…·Helena Mira

The paper identifies astrocyte subpopulations in the adult hippocampus based on cell surface markers and shows their distinct transcriptomic responses to aging.

DOI 10.1002/glia.70236

mousebulk RNA-seq

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NeuroscienceAging CellPeer-reviewedJan 18, 2026

Astrocyte senescence impairs synaptogenesis due to Thrombospondin-1 loss.

Stefano Ercoli, Lucía Casares-Crespo, Elena Juárez‐Escoto, Helena Mira

This study shows that astrocyte senescence in SAMP8 mice reduces synaptogenesis due to thrombospondin-1 loss, suggesting senescence prevention could restore synaptic function.

1 citation

mouseproteomics

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NeurosciencebioRxivPreprintMay 3, 2023

Autophagy is a cell-intrinsic driver of neural stem cell quiescence in hippocampal dentate gyrus development

Isabel Calatayud-Baselga, Lucía Casares-Crespo, Carmina Franch-Ibáñez…·Helena Mira

This study shows autophagy is essential for establishing quiescence in hippocampal neural stem cells during development.

DOI 10.1101/2023.05.03.539225

mouseexperimental assay

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