Cell BiologyNature CommunicationsPeer-reviewed
Vascular and Lymphatic Dysregulation via Non-EndoMT Col2a1 Signaling in Bisphosphonate-Related Osteonecrosis of the Jaw
Yixin Shi, Haiyang Sun, Zijian Guo…·Junyu Chen
This study identifies vascular and lymphatic dysfunction in BRONJ, revealing the COL2A1-CD44/SDC4 axis as a therapeutic target through multimodal analysis of mouse and human samples.