Author

Jorge Mauricio Reyes‐Ruiz

University of California, IrvineORCID 0000-0001-8609-9555Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Charles G. GlabeiD· 2 shared Ibtisam Baghallab· 1 shared J. Zhang· 1 shared Joshua Netanel· 1 shared Justyna SosnaiD· 1 shared Lukasz GoldschmidtiD· 1 shared Philip Louis FelgneriD· 1 shared Phuong Nguyen Mai Ho· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Charles G. GlabeORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJul 24, 2026

The diversity of disease-associated natural human antibody specificities declines dramatically in Alzheimers disease.

Jorge Mauricio Reyes‐Ruiz, J. Zhang, Joshua Netanel…·Charles G. Glabe

The paper investigates antibody specificity diversity in Alzheimer's disease and finds a 26-fold decline in diversity compared to cognitively normal individuals, with specific epitopes linked to amyloid proteins.

DOI 10.64898/2026.07.21.739870

humanproteomics

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NeuroscienceJournal of Biological ChemistryPeer-reviewedDec 9, 2020

Epitomic analysis of the specificity of conformation-dependent, anti-aβ amyloid monoclonal antibodies

Jorge Mauricio Reyes‐Ruiz, Rie Nakajima, Ibtisam Baghallab…·Charles G. Glabe

The paper maps epitopes of 28 anti-Aβ antibodies using epitomic analysis to understand their aggregation specificity and binding mechanisms.

16 citations

statistical model

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