BioinformaticsJournal of Chemical Information and ModelingPeer-reviewed
Cycledesigner Leveraging RFdiffusion and HighFold to Design Cyclic Peptide Binders for Specific Targets
Chenhao Zhang, Zhenyu Xu, Kang Lin…·Hongliang Duan
This study introduces cycledesigner, a method combining RFdiffusion, ProteinMPNN, and HighFold to design cyclic peptide binders for specific targets, followed by scoring functions for screening.
12 citations