Author

Lei Zhang

ORCID 0000-0001-8629-4385Unclaimed ORCID profile · follow to get notified of new preprints

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Lei Zhang18 papers · University of Minnesota

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

Bin FengiD· 1 shared Hao Li· 1 shared He Cao· 1 shared Junjie ZouiD· 1 shared Mingjun YangiD· 1 shared Sheng WangiD· 1 shared Yu LiiD· 1 shared Zijing LiuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBioinformatics

Bin FengORCID

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1 paper

Recent·Most cited

BioinformaticsPatternsPeer-reviewedSep 17, 2025

Hierarchical affinity landscape navigation through learning a shared pocket-ligand space

Bin Feng, Zijing Liu, Hao Li…·Sheng Wang

LigUnity is a foundation model that jointly embeds ligands and protein pockets into a shared space to improve affinity prediction in virtual screening and hit-to-lead optimization.

11 citationstop 3%

protein structuredeep learning

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