Cancer BiologyScience Translational MedicinePeer-reviewed
Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity
Erica Maria Pimenta, Amanda Garza, Sabrina Yvonne Camp…·Eliezer M. Van Allen
This study identifies epigenetic dysregulation of metabolic programs in liposarcoma, linking IGF1 loss and PPARG2 deficiency to dedifferentiation and proposing IGF1R-targeted therapy.