Author

Hiroshi Sakuma

Tokyo Metropolitan Institute of Medical ScienceORCID 0000-0001-8736-9027Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Haruo OkadoiD· 1 shared Masato HasegawaiD· 1 shared Masato HosokawaiD· 1 shared Shinobu HiraiiD· 1 shared Takaomi C. SaidoiD· 1 shared Takashi SaitoiD· 1 shared Tomoko TanakaiD· 1 shared

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2020-2020 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Haruo OkadoORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintApr 27, 2020

Early-life stress facilitates the development of Alzheimer's disease pathology via angiopathy

Tomoko Tanaka, Shinobu Hirai, Masato Hosokawa…·Haruo Okado

This study shows that early-life stress accelerates Alzheimer's disease pathology by inducing vascular changes and microglia activation in mice with an APP mutation.

DOI 10.1101/2020.04.27.062729

mouseexperimental assay

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