Kari Strouse

The paper introduces a structured pooling method for population-scale STARR-seq experiments, improving detection of rare regulatory variants by increasing signal-to-noise ratio and providing Bayesian effect size estimates.

The paper functionally measures allele-specific regulatory element activity across five human genomes to fine map causal variants in eQTLs and chromatin QTLs.

This paper introduces a consensus variant-to-function score to prioritize disease-causing variants, showing improved performance in heritability enrichment and fine-mapping.