BiochemistrybioRxiv
Conformation Selection by ATP-competitive Inhibitors and Allosteric Communication in ERK2
Jake W Anderson, David Vaisar, David N Jones…·Natalie G Ahn
This study identifies 14 ATP-competitive ERK2 inhibitors that select for the R-state conformation, revealing structural changes and allosteric communication mechanisms.
DOI 10.7554/elife.91507