Transfer learning enables prediction of CYP2D6 haplotype function
Gregory McInnes, Rachel Dalton, Katrin Sangkuhl, Michelle Whirl‐Carrillo, Seung‐been Lee, Philip S. Tsao, Andrea Gaedigk, Russ Biagio Altman, Erica L. Woodahl
This paper introduces a deep learning model, Hubble.2D6, to predict CYP2D6 haplotype function with 88% accuracy, aiding in drug response prediction.
PLoS Computational Biology · Nov 2, 2020Peer-reviewedBioinformatics