Author
University of WashingtonORCID 0000-0001-9869-1070Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Elizabeth X. Kwan, Gina M. Alvino, Kelsey L. Lynch…·M. K. Raghuraman
The paper shows that reducing rDNA copy number in S. cerevisiae changes its replication timing, delays genome replication, and links rDNA to cell cycle control via Cdc14p sequestration.
Daniel Taliun, Daniel Harris, Michael D. Kessler…·Ruth J. F. Loos
Over 400 million variants, 97% below 1% frequency, emerge from deep whole-genome sequencing of 53,831 diverse TOPMed participants; TOPMed haplotypes enable imputation down to ~0.01% frequency.
Gregory McInnes, Rachel Dalton, Katrin Sangkuhl…·Erica L. Woodahl
This paper introduces a deep learning model, Hubble.2D6, to predict CYP2D6 haplotype function with 88% accuracy, aiding in drug response prediction.