Yan Zhang

DPCGS links GWAS to single-cell transcriptomics to identify trait-associated cell subpopulations and regulatory programs with higher accuracy than existing methods.

CTDP identifies disease-associated cell types using scRNA-seq by integrating Lasso-regularized logistic regression and permutation testing, outperforming existing methods in accuracy and robustness.

The paper identifies novel lncRNAs associated with ventricular septal defect by integrating DNA methylation, gene expression, and lncRNA expression data from early embryos and VSD samples.