Richa Rashmi

This paper shows that delivering IFN2 via LNPs reprograms tumor and immune cells in ICI-resistant CRC, enhancing PD-1 blockade efficacy and reducing metastasis.

This study identifies IRF8 as a B cell-intrinsic regulator of antigen presentation that sustains CD8⁺ T cell antitumor immunity and predicts response to PD-1 blockade therapy.

The paper analyzes THAP9 and THAP9-AS1 across multiple cancers to show their expression correlates with poor patient survival and identifies coexpressed genes involved in DNA binding and viral infection.

The paper performs evolutionary analysis and in silico characterization of THAP9, identifying conserved regions, novel motifs, and potential cancer-related expression patterns.

The paper introduces SMA, an algorithm to predict G domains in G proteins by matching G-box patterns and inter-box spacer lengths, improving precision for family-specific motifs.