Author

David Rodríguez-Crespo

University of FribourgORCID 0000-0001-9014-5067Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Assay:DNA methylation· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Chantal WickyiD· 3 shared Magali NancheniD· 2 shared Shweta RajopadhyeiD· 2 shared Emily R. TroemeliD· 1 shared Michael StumpeiD· 1 shared Peter MeisteriD· 1 shared Vladimir LažetićiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 14 mutual co-author links

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3 shared papersBiochemistry

Chantal WickyORCID

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3 papers

Recent·Most cited

The transcription factor LSL-1 interacts with the chromatin factors HIM-17, XND-1 and BRA-2 to promote the germline-specific transcriptional repertoire and to safeguard germ cell fate in C. elegans

Magali Nanchen, David Rodríguez-Crespo, Michael Stumpe, Chantal Wicky

The paper identifies LSL-1's interaction with chromatin factors to maintain germline transcriptional programs and cell fate in C. elegans.

bioRxiv · Apr 7, 2026 · PreprintBiochemistry

The chromatin remodeler LET-418/Mi-2 regulates the intracellular pathogen response in the C. elegans intestine

Shweta Rajopadhye, Vladimir Lažetić, David Rodríguez-Crespo, Emily R. Troemel, Peter Meister, Chantal Wicky

This study identifies LET-418 as a regulator of intracellular pathogen response in C. elegans intestine by analyzing its target genes and functional effects on immune response genes.

BMC Genomics · Oct 21, 2025Peer-reviewedGenomics

The zinc-finger transcription factor LSL-1 is a major regulator of the germline transcriptional program in C. elegans

David Rodríguez-Crespo, Magali Nanchen, Shweta Rajopadhye, Chantal Wicky

This study identifies LSL-1 as a key transcriptional activator of germline genes in C. elegans, showing its role in meiotic progression and gene regulation through interaction with heterochromatin proteins.

Genetics · Mar 9, 2022Peer-reviewedGenetics