Molecular BiologybioRxivPreprint
Copper deficiency drives OXPHOS impairment and mitochondrial hyperfusion via MTCH2 in skeletal muscle
Young-Seung Lee, Hee Soo Kim, Phuc L. Nguyen…·Tae Il Jeon
This study shows that copper deficiency in skeletal muscle leads to mitochondrial dysfunction and hyperfusion via MTCH2, and restoring copper rescues these defects.
DOI 10.1101/2025.11.19.688750