Author

Chris W. Lee

Atlantic Health SystemORCID 0000-0001-9068-5274Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Aimee R. Herdt· 1 shared Azucena Pérez‐CañamásiD· 1 shared Hideyuki TakahashiiD· 1 shared Hongping Ye· 1 shared Hui Chin PengiD· 1 shared Kwok‐Fai LauiD· 1 shared Michael H. GelbiD· 1 shared Stephen M. StrittmatteriD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

Aimee R. Herdt

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2 papers

Recent·Most cited

Cell BiologyJournal of Biological ChemistryPeer-reviewedMay 29, 2025

Expression study of Krabbe Disease GALC missense variants -- Insights from quantification profiles of residual enzyme activity, secretion and psychosine levels

Hui Chin Peng, Ying‐Wai Lam, Kwok‐Fai Lau…·Chris W. Lee

This study quantifies the functional impact of GALC missense variants in Krabbe disease, showing strong correlations between residual enzyme activity, clinical severity, and psychosine levels.

4 citations

humanproteomics

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NeuroscienceCommunications BiologyPeer-reviewedSep 5, 2024

Lysosomal TMEM106B interacts with galactosylceramidase to regulate myelin lipid metabolism

Hideyuki Takahashi, Azucena Pérez‐Cañamás, Chris W. Lee…·Stephen M. Strittmatter

This study identifies TMEM106B's role in regulating myelin lipid metabolism by interacting with galactosylceramidase in TMEM106B-deficient mice.

15 citations

mouseexperimental assay

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