Author

Jennifer E. C. Fragale

Rutgers, The State University of New JerseyORCID 0000-0001-9074-4879Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:rat· 2

Frequent Co-Authors

Gary Aston‐JonesiD· 2 shared Morgan H. JamesiD· 2 shared Shayna L. O’ConnoriD· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersNeuroscience

Gary Aston‐JonesORCID

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2 papers

Recent·Most cited

Intermittent self-administration of fentanyl induces a multifaceted addiction state associated with persistent changes in the orexin system.

Jennifer E. C. Fragale, Morgan H. James, Gary Aston‐Jones

This study shows that intermittent fentanyl self-administration in rats leads to addiction-like behaviors that are reversed by an orexin-1 receptor antagonist.

Addiction Biology · Aug 14, 2020Peer-reviewedNeuroscience

The dual orexin/hypocretin receptor antagonist suvorexant reduces addiction-like behaviors for the opioid fentanyl

Shayna L. O’Connor, Jennifer E. C. Fragale, Morgan H. James, Gary Aston‐Jones

This study tests suvorexant's ability to reduce fentanyl-related addiction-like behaviors in rats, finding it effective in decreasing motivation and reinstatement without affecting locomotion or natural rewards.

bioRxiv · Apr 25, 2020 · PreprintNeuroscience