Author

Andrew H. Sims

Edinburgh Cancer ResearchORCID 0000-0001-9082-3665Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Abdelkader Essafi· 1 shared Ajit J. NirmaliD· 1 shared Alexander L. R. LubbockiD· 1 shared Bret S.E. HealeiD· 1 shared Dominic Pearce· 1 shared Erola Pairo‐CastineiraiD· 1 shared Ian M. OvertoniD· 1 shared Jeremy A. OweniD· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSystems Biology

Abdelkader Essafi

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2 papers

Recent·Most cited

Functionally Coherent Transcription Factor Target Networks Illuminate Control of Epithelial Remodelling

Ian M. Overton, Andrew H. Sims, Jeremy A. Owen, Bret S.E. Heale, Matthew J. Ford, Alexander L. R. Lubbock, Erola Pairo‐Castineira, Abdelkader Essafi

The paper introduces NetNC, a tool to identify functionally coherent TF targets, showing it effectively finds neutral binding and reveals new gene functions in EMT processes.

Cancers · Sep 30, 2020Peer-reviewedSystems Biology

Continuous Biomarker Assessment by Exhaustive Survival Analysis

Dominic Pearce, Ajit J. Nirmal, Tom C. Freeman, Andrew H. Sims

The paper introduces survivALL, an R package for continuous biomarker assessment through survival analysis, enabling reliable evaluation of gene expression cut-points across datasets.

bioRxiv · Mar 2, 2018 · PreprintBioinformatics