Author

Ian M. Overton

Queen's University BelfastORCID 0000-0003-1158-8527Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:database / resource· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Abdelkader Essafi· 1 shared Alexander L. R. LubbockiD· 1 shared Andrew H. SimsiD· 1 shared Bret S.E. HealeiD· 1 shared Duong H.T. VoiD· 1 shared Erola Pairo‐CastineiraiD· 1 shared Gerard McGleave· 1 shared Helen G. ColemaniD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperSystems Biology

Abdelkader Essafi

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3 papers

Recent·Most cited

BioinformaticsGigaSciencePeer-reviewedDec 28, 2022

Strategies and Techniques for Quality Control and Semantic Enrichment with Multimodal Data: A Case Study in Colorectal Cancer with eHDPrep

Tom M Toner, Rashi Pancholi, Paul Miller…·Ian M. Overton

The paper introduces eHDPrep, an R package for health data preparation, demonstrating its use on a colorectal cancer dataset to improve data quality and semantic enrichment.

3 citations

humanelectronic health records

𝕏 PostBluesky

Systems BiologybioRxivPreprintApr 22, 2021

Immune cell networks uncover candidate biomarkers of cancer immunotherapy response

Duong H.T. Vo, Gerard McGleave, Ian M. Overton

The paper identifies immune cell-specific gene networks associated with response to nivolumab therapy in melanoma and highlights B cell genes as potential prognostic biomarkers.

DOI 10.1101/2021.04.22.440902

humanbulk RNA-seq

𝕏 PostBluesky

Systems BiologyCancersPeer-reviewedSep 30, 2020

Functionally Coherent Transcription Factor Target Networks Illuminate Control of Epithelial Remodelling

Ian M. Overton, Andrew H. Sims, Jeremy A. Owen…·Abdelkader Essafi

The paper introduces NetNC, a tool to identify functionally coherent TF targets, showing it effectively finds neutral binding and reveals new gene functions in EMT processes.

9 citations

humanmouse

𝕏 PostBluesky