Author

Alina M. Hamilton

University of North Carolina at Chapel HillORCID 0000-0001-9121-7114Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Research Focus:deconvolution· 1

Frequent Co-Authors

Arjun BhattacharyaiD· 2 shared Melissa A. TroesteriD· 2 shared Michael I. LoveiD· 2 shared Eugene J. PietzakiD· 1 shared Helena F. FurbergiD· 1 shared Katherine A. HoadleyiD· 1 shared Mark P. PurdueiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersBioinformatics

Arjun BhattacharyaORCID

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2 papers

Recent·Most cited

BioinformaticsNucleic Acids ResearchPeer-reviewedJan 13, 2021

DeCompress: tissue compartment deconvolution of targeted mRNA expression panels using compressed sensing

Arjun Bhattacharya, Alina M. Hamilton, Melissa A. Troester, Michael I. Love

DeCompress improves deconvolution of targeted mRNA panels by expanding feature space with reference data, achieving better cell-type proportion estimation and identifying a tumor-specific cis-eQTL for CCR3.

9 citations

humanbulk RNA-seq

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GenomicsBriefings in BioinformaticsPeer-reviewedAug 11, 2020

An approach for normalization and quality control for NanoString RNA expression data

Arjun Bhattacharya, Alina M. Hamilton, Helena F. Furberg…·Michael I. Love

This paper develops a normalization and quality control approach for NanoString RNA data, showing improved handling of technical variation without loss of biological variation.

122 citationstop 3%

humanbulk RNA-seq

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