Author

Chloe A Hecht

Stanford MedicineORCID 0000-0001-9248-9576Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Dario R. AlessiiD· 1 shared Ebsy JaimoniD· 1 shared Emily A. DickieiD· 1 shared Francesca TonelliiD· 1 shared Matthew TayloriD· 1 shared Melanie Wightman· 1 shared Paweł LisiD· 1 shared Prosenjit PaliD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Dario R. AlessiORCID

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1 paper

Recent·Most cited

NeuroscienceScience AdvancesPeer-reviewedDec 13, 2023

Parkinsons VPS35 mutation induces LRRK2 mediated lysosomal association of RILPL1 and TMEM55B

Prosenjit Pal, Matthew Taylor, Yuko P. Y. Lam…·Dario R. Alessi

This study shows that the VPS35[D620N] mutation causes lysosomal dysfunction, activates LRRK2, and promotes the lysosomal association of RILPL1 and TMEM55B through phosphorylation of Rab proteins.

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mouseproteomics

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