Author

Qihan Jin

Westlake UniversityORCID 0000-0001-9271-4403Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:protein design· 2 Assay:protein structure· 2 Approach:statistical model· 1

Frequent Co-Authors

Chentong WangiD· 2 shared Longxing CaoiD· 2 shared Minchao FangiD· 2 shared Yitao KeiD· 2 shared Dachuan CheniD· 1 shared Fengbai Lian· 1 shared Jiao LiuiD· 1 shared Jinyang Liao· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBioinformatics

Chentong WangORCID

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2 papers

Recent·Most cited

De novo design of ligand binding and sensing with a physics based generative approach

Yanzhe Zhang, Yitao Ke, Rui Zhi, Qihan Jin, Yiqin Feng, Chentong Wang, Minchao Fang, Jinyang Liao, Dachuan Chen, Jiao Liu, Longxing Cao

This paper introduces a physics-based generative method for designing ligand-binding proteins and demonstrates its application in creating biosensors for small molecules and metal ions.

bioRxiv · Jul 14, 2026 · PreprintBioinformatics

HalluDesign: Protein Optimization and de novo Design via Iterative Structure Hallucination and Sequence Design

Minchao Fang, Chentong Wang, Jungang Shi, Fengbai Lian, Qihan Jin, Zhe Wang, Yanzhe Zhang, Peipei Chen, Zhanyuan Cui, Yanjun Wang, Ze Zhang, Yitao Ke, Qingzheng Han, Longxing Cao

HalluDesign optimizes and designs proteins using iterative structure hallucination and sequence design, achieving high success rates and structural accuracy in various tasks.

bioRxiv · Nov 8, 2025 · PreprintBioinformatics