Molecular BiologybioRxivPreprint
D-lactate derived from intestinal bacteria drives lysine D-lactylation to modulate transcription in liver cells
Yong Zang, Jianji Zhang, Mingxin Xia…·Kai Zhang
This study shows that D-lactate from intestinal bacteria induces lysine D-lactylation in liver cells, modulating transcription and inhibiting hepatocellular carcinoma cell proliferation.