ImmunologyThe Journal of Experimental MedicinePeer-reviewed
IRF7 controls spontaneous autoimmune germinal center and plasma cell checkpoints
Adam J. Fike, Kristen N Bricker, Michael V. Gonzalez…·Ziaur S. M. Rahman
This study identifies B cell-intrinsic and -extrinsic mechanisms by which IRF7 promotes spontaneous autoimmune germinal center and plasma cell responses, autoantibody production, and SLE development.