Michael V. Gonzalez

This study shows that reduced hepatic phosphatidylcholine biosynthesis leads to copper deficiency, which promotes MASH through disrupted copper distribution and fibrogenesis.

The paper identifies NFAT inhibition as a cause of reduced uterine natural killer (uNK) cells and pregnancy complications in humans through analysis of uterus transplant recipients.

This study identifies disrupted lymphocyte chemotaxis in idiopathic multicentric Castleman disease, linking dysregulated chemokine production to germinal center dysfunction and lymphadenopathy.

The paper tracks GM-CSF expression in immune cells using reporter mice, identifying diverse sources and transient expression patterns in health and autoimmune neuroinflammation.

This study identifies B cell-intrinsic and -extrinsic mechanisms by which IRF7 promotes spontaneous autoimmune germinal center and plasma cell responses, autoantibody production, and SLE development.

This study shows that RUNX1 haploinsufficiency reduces megakaryocyte-biased hematopoietic progenitor cells and identifies drug targets to correct this defect.

LinkedSV detects mosaic structural variants from linked-read sequencing data, outperforming existing tools and identifying SVs missed by conventional sequencing methods.