Characterization and Mitigation of Fragmentation Enzyme-Induced Dual Stranded Artifacts
Charles T. Gregory, Apollinaire Ngankeu, Shelley J. Orwick, Esko Antero Kautto, Jennifer Ann Woyach, John C. Byrd, James Stewart Blachly
This paper identifies and mitigates sequencing artifacts caused by fragmentation enzymes, presenting FADE software to remove these artifacts and reduce their impact on downstream analyses.
NAR Genomics and Bioinformatics · Oct 2, 2020Peer-reviewedBioinformatics