Cristina Sisu

The paper surveys pseudogene expression in human and macaque brains compared to 29 other tissues, finding elevated and consistent brain expression and associations with neuropsychiatric disorders.

The paper expands the lncRNA catalog using capture long-read RNA sequencing, significantly increasing the number of annotated transcripts in human and mouse genomes.

This paper compares 2D and 3D ovarian cancer models through a meta-analysis, identifying differentially expressed genes and pathways, and highlighting the benefits of 3D models in capturing tumor biology.

The paper annotates pseudogenes in the mouse genome and strains, finding similar overall characteristics to humans but distinct age distributions and transcriptional patterns.

The paper reanalyzes the CHESS database's new protein-coding predictions and finds most are false positives due to homology errors and lack of experimental evidence.

The paper compares genome assemblies of Mus caroli and Mus pahari with Mus musculus and Rattus norvegicus to reveal lineage-specific evolutionary mechanisms, particularly repeat-associated processes.

The paper presents full-length de novo genome assemblies for 16 inbred mouse strains, identifying strain-specific haplotypes and novel functional loci, including a large unannotated gene with potential developmental roles.