Hepatic management of toxic sterols after acute deletion of Cyp51 from cholesterol synthesis
Tinkara Kreft, Kaja Blagotinšek Cokan, Cene Skubic, Tadeja Režen, Martina Perše, Karmen Wechtersbach, Nika Kojc, Jera Jeruc, Željko Debeljak, Marija Heffer, Madlen Matz‐Soja, Damjana Rozman
This study develops an inducible liver-specific Cyp51 knockout mouse model to investigate how acute cholesterol synthesis disruption affects liver pathology and cellular responses.
Journal of Biological Chemistry · Jan 24, 2026Peer-reviewedBiochemistry