Damjana Rozman

GD3 synthase deficiency disrupts Na+/K+-ATPase and plasma membrane Ca2+-ATPase function in mouse brain

This study shows GD3S deficiency disrupts NKA and PMCA function in mouse brain by altering ganglioside and lipid raft composition, suggesting therapeutic potential through exogenous ganglioside administration.

Hepatic management of toxic sterols after acute deletion of Cyp51 from cholesterol synthesis

This study develops an inducible liver-specific Cyp51 knockout mouse model to investigate how acute cholesterol synthesis disruption affects liver pathology and cellular responses.

Stable reference genes for 24-hour circadian profiling of core clock genes in the blood of obstructive sleep apnea patients

The paper identifies ACTB and RPL13A as stable reference genes for circadian gene expression analysis in blood samples from OSA patients.

Common transcriptional programme of liver fibrosis in mouse genetic models and humans

The paper identifies a common transcriptional programme of liver fibrosis across mouse models and humans, revealing shared pathways and metabolic subtypes.