Molecular BiologybioRxivPreprint
Reverse gyrase and 3D genome architecture suppress hyperthermophile genome instability arising from horizontal gene transfer
Kodai Yamaura, Naomichi Takemata, Takeshi Yamagami…·Haruyuki Atomi
This study identifies reverse gyrase's role in preventing genome instability in hyperthermophiles by suppressing AT-rich gene clustering and DNA melting associated with horizontal gene transfer.
DOI 10.64898/2025.12.08.692931