BioinformaticsNature Machine IntelligencePeer-reviewed
Epitope-anchored contrastive transfer learning for paired CD8+ T cell receptor-antigen recognition
Yumeng Zhang, Zhikang Wang, Yunzhe Jiang…·Jiangning Song
This paper introduces EPACT, a deep-learning framework for predicting TCR-antigen binding pairs, showing high accuracy in epitope recognition and TCR repertoire analysis.